This means that, if you chose to test for these other conditions (and I can understand why many women opt for this when NIPT is marketed as being 99% accurate) and you get a high chance result, there is a high probability that the result will turnout to be wrong. This is probably because the limited research that has taken place has shown that NIPT performs poorly for many of these conditions. Information relating to the accuracy of NIPT for these conditions is often missing from websites and public materials. These include those caused by unusual numbers ofthe sex (X and Y) chromosomes, such as Turner syndrome and Triple X syndrome,and those caused by small bits of DNA missing, called microdeletions, such as Prader-Willi syndrome and 5p deletion syndrome. Many clinics and NIPT test providers offer the option of testing for a range of other, often very rare, genetic conditions. Offering NIPT where the accuracy is low or unknown Yet, in the private sector, you’re lucky if they have included the web address of a Down’s syndrome organisation.Īt the Nuffield Council, we believe it's only ethical to offer NIPT within an environment that enables women and couples to make informed choices, and the provision of high quality information about the tested-for conditions is crucial to this.ģ. Public Health England has spent a year consulting with support organisations and families of people with the conditions to help them describe, as neutrally as possible, what having a child with one of these conditions might mean. In the NHS, the development of balanced and up-to-date information about the conditions has been central to the aim of ensuring women and couples make informed decisions about NIPT. Very fewprivate clinics or test providers include information about Down’s syndrome, Edwards’ syndrome and Patau’s syndrome in their marketing and information materials. Poor information about the tested-for conditions Some companies give people’s results as being ‘positive’ or ‘negative’, which as you can see is highly misleading or, at best, confusing. So, if you want to know for sure, you will also need to have a diagnostic test such as amniocentesis. For Patau’s syndrome, there is a 1 in 2 (50%) chance the result is wrong, and for Edwards’ syndrome, it’s a 3 in 5 (60%) chance. If you receive a high chance result for Down’s syndrome, there is a 1 in 5 (20%) chance that the result is wrong and your fetus does not have the condition. Sometimes NIPT gives a high chance result when the fetus does not actually have the condition. But as the conditions affect less than 1% of all children born, a dummy test that gave everybody a low chance result would be 99% accurate.Ī more helpful statistic is the positive predictive value. I think most people would assume that this means their result will tell them pretty much for sure whether their fetus has one of the conditions or not. The websites of most private providers state that NIPT is ‘99% accurate’ or has ‘99% sensitivity’. Disappointingly, despite our best efforts to raise these issues, little has changed. We highlighted some serious issues with how some (not all) clinics and NIPT test providers are marketing and offering NIPT in the UK. The Nuffield Council on Bioethics’ 2017 report on the ethical issues raised by NIPT discussed the offer of NIPT in the private sector. It is pretty accurate for Down’s, Edwards’ and Patau’s syndromes even if you are not in the higher chance category, and the test is available from around 9 weeks of pregnancy. However, NIPT can already be accessed through numerous private clinics and hospitals across the UK for around £500. NIPT for these conditions has recently become available to pregnant women in the higher chance category in the NHS in Wales, and it has been promised to women in England and Scotland in the near future. You still get some false positive results, but far fewer than with older screening tests. NIPT has been shown in multiple studies to be very good at identifying the most common chromosomal conditions – Down’s syndrome, Edwards’ syndrome and Patau’s syndrome – particularly in women who have a higher chance of having a fetus with one of these conditions. This is a newish kind of screening test in which a blood sample from a pregnant woman is used to test for a range of genetic conditions in the fetus, with varying levels of certainty. ![]() Disagreements in the care of critically ill children.
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![]() It can then be quite an ordeal to reinstate the account to the right owner. Usually, Facebook takes these fake scammer accounts down very quickly.īe sure to report the right one! In their haste to do the right thing, some people mistakenly report the legitimate account. Using the reporting tools, they will need to report the "Fake" account to Facebook as an impersonation account. Double check that it is a scammer, not them who messaged you. There is a risk that other friends will also be contacted and scammed.Ĭontact your friend on their legitimate account (be sure it's not the fake one) or via another method, text, phone or email. What Can You Do If Your Friend Has Been Cloned?Īlert your friend as soon as possible. The purpose is usually to defraud you to gain your Facebook or bank details to hack your account, or sell your details on the black market for further fraud. "No time to waste, time is running out!!!" etc. They then will pressure you to give out all your personal details and try to get you to commit right away with the support of your Fake friend. They may then connect you with another profile pretending to be the salesperson for the deal or competition. If they send you a message, the scammer, after some preamble, will start messaging you about some incredible competition or deal. If the scammer has cloned your friend's profile, they usually private message all the publically available friends they can see via the original account. How would you know if one of your Facebook friend's profiles has been cloned? Help for hacked Facebook Accounts Here: HAS YOUR FRIEND'S FACEBOOK BEEN "CLONED"? You can certainly change your password, but it may not be necessary in this case as the account may have been copied rather than hacked. If victims suspect they have been hacked, they often try to change their password to block the hacker. However, with this particular scam, your account has been copied/cloned, NOT hacked. Many victims of this cloning scam think their account has been hacked when someone informs them that their Facebook account is sending out scams. The messages usually include scam offers or fake competitions to win trips or money to steal from or hack an account. They then send friend requests or messages to the Facebook friends of the original account from the fake account. The Facebook Profile Clone ScamĪ common Facebook scam spread by unprotected friends lists is when a scammer "Clones" or copies a Facebook profile. If scamming you is too complicated, the scammer will move on to the next person with minimal privacy settings set and their friends list open. Setting your friend list to "Only Me" protects you from opportunist scammers or stalkers. If your Facebook friends list is not private, set to "Only Me", you will be more of a target for scammers, and so will your Facebook friends. ![]() In the Kanto region, unagi is eaten in the form of “unaju” (or unadon), which is unagi served over rice, at specialty restaurants called “Unagiya”. Of course, unagi sushi exists in Japan, but it is more common in sushi shops in the Kansai region and as nigiri sushi at the conveyor belt sushi restaurants. However, in a Sushiology context, they are completely different types of toppings.įirst of all, 99% of sushi restaurants that specifically serve Edo-style sushi, do not offer unagi sushi. Basically, unagi lives in freshwater regions and conger eel live in the sea. So what is the difference between eel and conger eel?īiologically, they are both in the “unagi” or eel family. Next, the “ana” in Anakyu is an abbreviation of “anago” (Japanese conger eel) and anakyu is a sushi roll in which Japanese conger eel, Japanese cucumber and sushi rice are rolled up in nori. In other words, a unakyu roll is a sushi roll made by wrapping Japanese eel, Japanese cucumber and sushi rice in nori (seaweed paper). The “una” in Unakyu is an abbreviation of “unagi” (Japanese eel) and “kyu” is an abbreviation of “Kyuri” (Japanese cucumber). The difference between unakyu roll (unakyu maki) and anakyu roll (anakyu maki) *Sukimi refers to a thin slice of the fish from which the meat between the muscle and the fat remaining on the back of the skin is cut away.Ģ-1-5 Anakyu maki (cucumber and conger eel roll)įinely sliced conger eel is combined with cucumber, then wrapped in seaweed. ![]() The pickled radish has a refreshing flavor and matches perfectly with the thick fat of the tuna. *Kampyo is the white flesh of the bottle gourd, which is cut into long strips, as if peeling it, then cut so it looks like strings, then laid out to dry, perhaps in the sunshine or hot air.Ģ-1-4 Torotaku maki (tuna and pickled radish roll)Ĭhopped pickled radish is combined with sukimi* to form the center of this seaweed roll. Most people already know the center of this roll is tuna.Ī seaweed roll with sweet, boiled Kanpyo* in the center. (It has been this way for many years, but the reason is not certain) Let me start by introducing the famous types of skinny rolls.Ĭucumber is cut into long strips and a few of these strips, seasoned with white sesame seeds, are rolled into seaweed. Tekka-maki and Kappa-maki are rolled into square shapes, cut into 6 pieces, and then served to stand on the ends so that the red and green colors are visible. For example, Kanpyo-maki is rolled so that the cross-section is round, cut into 4 pieces, and then presented on its side. One of the characteristics of Hoso-maki is that the way it is cut and served differs depending on the ingredients inside. ![]() Around 80 grams of sushi rice is used for one Hoso-maki roll. The core of these rolls may be cucumber, tuna, dried gourd, pickled daikon radish, natto (fermented soybeans), or something else, and the rolls are named for these fillings. Rolls where one sheet of nori is grilled before use and then cut in half are called “Hoso-maki”. ![]() Zenkei is cut to a variety of other sizes depending on how it is used. The basic size of one piece of nori (dried seaweed) is L 210 x W 190 mm. Makizushi is broadly categorized as Hoso-maki (thin rolls), Futo-maki (thick rolls), Saiku-maki (decorative rolls) and Temaki (hand rolls), which are actually a type of skinny rolls. But the vinegar rice in these pieces is rolled by hand so wouldn’t that mean it’s one type of nigiri-sushi?! You may be interested to know that salmon roe and sea urchin gun-kan pieces that are wrapped in seaweed aren’t rolled by hand like this, so some people don’t consider them to be nigiri-sushi. This type of sushi consists of placing a fish fillet or another topping on top of special vinegar rice, then pressing it by hand. The most famous of these is nigiri-sushi, and it is what most out-of-towners are referring to with the word “sushi”. If you add in the local forms of sushi, there are as many types as there are regions. The common seven types of sushi that every Japanese person knows of include Nigiri zushi (Nigiri sushi), Makizushi (Makisushi), Chirashizushi (Chirashi sushi), Inarizushi (Inari sushi), Sushi rolls, Oshizushi and Others. Let’s take a closer look at the different types of sushi! Latest Version Release Added On: 07th Aug 2019.Compatibility Architecture: 32 Bit (x86) / 64 Bit (圆4).Setup Type: Offline Installer / Full Standalone Setup.Software Full Name: Aiseesoft Screen Recorder Pro 2019.You can also download ThunderSoft GIF to Video Converter 2017.įeatures of Aiseesoft Screen Recorder Proīelow are some noticeable features which you’ll experience after Aiseesoft Screen Recorder Pro free download.Īiseesoft Screen Recorder Pro Technical Setup Details It has a shortcut button for quick recording and accessing. 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Community theatre in downtown Charleston, located on 20 Queen Street and celebrating its 75th year this season 2006- 2007. ![]() 7 at 9 p.m., check out Jeremy McLellan and on Fri. The Queen Street Comedy Series, hosted by Bill Davis, features local comedians performing on the first Friday of each month. The Charlestonian, Charleston Chamber of Commerce, November 1947. 27, head over for a performance from Doug Jones Everybody Doug Jones, Forty Mile Detour, and Wild Ponies. Columbia: University of South Carolina Press, 2007. 28, you can hear from Mike Farris and the Fortunate Few, and on Thurs. In 1986, after another dramatic renovation, The Footlight Players moved into the old cotton warehouse at 20 Queen St., where it remains to this day. Tonight, Pierce Edens and Johnny Holliday perform. Restaurants near Footlight Players, Charleston on Tripadvisor: Find traveler reviews and candid photos of dining near Footlight Players in Charleston, South Carolina. The Queen Street Harmony Series, held on Tuesdays or Thursdays and featuring live and often local music. In a press release, Footlight Players announces, “The Board of Directors is thrilled to announce that the building will once again don the historic name of Queen Street Playhouse in honor of the company’s initiative to transform the facility into a performing arts event center, the only one of its kind in downtown Charleston.”Īnd while Footlight assures Charleston that “Footlight Players is not going anywhere,” they say they are most certainly changing things up and “expanding their repertoire under a larger umbrella.”Ĭheck out upcoming repertoire expansions including: Footlight Players is the oldest theater company in Charleston, in operation since 1931 they’ve occupied the old cotton warehouse at 20 Queen St. will continue to operate as the home of the Footlight Players company, the venue is introducing more varied productions under its new moniker, from a ‘Queen Street Harmony’ series, presented by Awendaw Green a comedy series from Bill Davis and poetry nights with Marcus Amaker. Today Footlight Players announced that, in an effort to “return to its roots,” the company is rebranding their space, located at 20 Queen St., as the Queen Street Playhouse. ![]() Talk to your OT about your child’s school /preschool/ day-care. In some instances a lifting hoist may be recommended by the hospital OT. The weight of the plaster puts too much pressure on your child’s pelvis and spine.Ĭarry your child as close to you as possible when you are carrying him/her. Never lift your child from under the arms. Handling the broomstick can weaken the plaster. Always have one hand on the plaster (supporting the weight of the plaster) and one hand behind your child (supporting their back).ĭo not lift by the broomstick. When lifting your child, support both the plaster and your child. The plaster will also add to the weight of your child. The shape of the plaster and the child’s inability to move, make lifting and carrying difficult. The hospital occupational therapist can help with ideas for play and positioning at home. Your child will need help to be in the best position to enjoy each play situation. The hospital occupational therapist will discuss the best option for your child. Older children can use a urine bottle, slipper pan, or commode chair for toileting. These will need to be changed frequently to avoid the plaster becoming wet. Your child can continue to wear nappies with the broomstick plaster. Alternatively, this can be done over a sink/bowl with 2 people to help. Make sure that the plaster does not get wet.ĭry shampoo can be used for hair washing. Please note that the plaster may make your child warmer, so you will need to dress them accordingly. underwear, shorts or pants)īaggy shorts or pants with a split in one side (fixed with Hook and Loop tape, press studs or ties). 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Make sure feet are not pressed on the bed and your child’s head is turned to the sideĬheck your child’s skin around the plaster every morning and night. ![]() Place a pillow under your child’s chest and hips to support them and the plaster Making sure that your child’s feet or ankles are not touching the mattress by placing rolled up towels under their ankles. Having children sleep in one position during the night Consider:Ĭhanging positions every 2-4 hours: back, side or tummy, during the day Your child will need to change positions regularly to relieve pressure and to prevent skin irritation/sores. The hospital therapists will show you how to position your child in sitting and lying. A broomstick plaster is used to keep the hips and knees in the right position after a number of different surgical procedures. A broomstick plaster cast is used to keep the legs as still as possible, in the most correct position for healing. A wooden broomstick is used between their legs to hold your child’s legs apart. A “Broomstick” plaster holds your child’s legs apart with both legs in a plaster. ![]() The closest LoopBack 4 comes to being a tangible entity is the loopback-next monorepo, and maybe the lb4 CLI. There is no LoopBack 4 on NPM, like how there is LoopBack 3 ( loopback), and there is nothing that can be downloaded that would constitute as LoopBack 4. LoopBack 4 as an entity does not exist.There are two things you must know right at the beginning. Here's my take on the LoopBack 4 tutorial. On my website I am free from such guidelines, which allow me to write write tutorials the way I think they should be structured and written. However, official documentation follow certain guidelines and generally don't allow for such an approach. In my opinion, a semi-informal presentation is the best format for teaching. This post is the first among many that I will be writing on LoopBack. While we are actively addressing it and have made documentation improvement as one of our highest priorities this year, I am taking up "better learning materials for LoopBack" as a personal goal and plan to completely change the perception of LoopBack. If you know JavaScript already, it can be leaned in a day.Īs one of the core developers of LoopBack, a very frequent complaint I hear is about our "not-so-great" documentation. If you are totally new to TypeScript, I suggest you learn it and come back. Create the https server for the application. See for more details.A basic level knowledge of TypeScript is a minimal requirement for using LoopBack 4.OAuth 2.0 states that the authorization server MUST require the use of TLS with server authentication for any request sent to the authorization and token endpoints. There are two steps involved here: We customize server/server.js to add specific features for the gateway. The application is initially scaffolded using slc loopback command. The architecture is illustrated in the diagram below. A loopback application (api server) serving the REST APIs.A loopback application (api gateway) that bridges the client application and the backend api.A client application that invokes REST APIs.The test scenario consists of three components: Reverse proxy: forward the requests to the server that hosts the api endpoint. ![]() Rate limiting: controls how many requests can be made within a given time period for identified api consumers.oAuth 2.0 based authentication & authorization: authenticate client applications and authorize them to access protected endpoints with approval from resource owners.HTTPS: make sure all communication will be done with https.The gateway supports basic features listed below: Loopback-gateway is an example application to demonstrate how to build an API gateway using LoopBack. In this tutorial, we’ll build a simplified version of API gateway using LoopBack. The API gateway sits as an intermediary between the many consumers of APIs – API clients and the many producers of the APIs on the backend – API servers. Learn more… What is an API gateway?Īn API gateway is a component within systems architecture to externalize, secure and manage APIs. What’s LoopBack? It’s an open source Node.js framework for developing, managing and scaling APIs. In this blog we’ll show you how to get started with a sample application to test out the features of the gateway. The LoopBack API Gateway is open source and is the “minimum viable product” (MVP) that covers key use cases piloted with our co-development partners. In case you missed it, today we announced the availability of the open source LoopBack API Gateway. Read this announcement blog to learn more about the latest version. 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Control Page viewer for custom user defined UI pages View all custom 3rd Party Plugin device information Real time updates of all variable values Real time updates of all hardware (brightness, temperature, active zone, sensor values, etc.) View any Indigo defined Variables (house mode, etc.) Execute any Indigo defined Action Groups One touch UI controls for lighting, appliances, sprinklers, ceiling fans, and HVAC Instant control and access to all your smart home devices See MAC REQUIREMENTS below for more details.įor support, please contact us directly using the contact form on our website rather than requesting help via a review. Indigo is NOT FREE, although there is a 30 day free trial available. 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In "Triple Trouble", his skeleton looks like it's outgrowing the skin, with his eyelids stretching past his eye sockets, and his Slasher Smile being so wide that it exposes his jawbone.A few of his animations in "You Can't Run" show the flesh inside of his mouth as horrifically torn up.As the hands' positions change, it almost gives the impression that something's trying to climb out of his mouth. He has an additional pair of hands inside his body, as seen in his right and down poses, as well as the ending cutscene.Big "WHAT?!": Xenophanes lets one out in the official "Final Escape" once Boyfriend goes super like he did with Fleetway before him, complete with a perplexed face in the music video.His appearances in the 3.0 build, bar "Triple Trouble", have also been redrawn, alongside getting visibly angry after the 16-bit segment of "You Can't Run." Art Evolution: Sonic.exe had a few visual upgrades in 2.0 and it applies in each of his songs as the main story progresses, his artwork becomes more detailed and unsettling to watch. ![]() Always a Bigger Fish: The all powerful nigh-reality warper is easily held off by a 19-year old demon girl.Alien Blood: As Xenophanes, the blood coming from his eyes becomes a darker shade of pink matching his crystalline quills as opposed to the blood-red that stains his hands.He also would’ve let one out after his first verse in “Triple Trouble Encore” without the sinister laughter afterwards with considerably more vitriol towards BF. In this case, the quote is said in a very deep and menacing voice rather than simply being text on screen, and it is followed by a particularly eerie laugh. 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